Coenzyme Q: potentially useful index of bioenergetic and oxidative status of spermatozoa.

نویسندگان

  • A G Angelitti
  • L Colacicco
  • C Callà
  • M Arizzi
  • S Lippa
چکیده

The concentration of coenzyme Q10 (CoQ10), a key intermediate of the mitochondrial respiratory chain, was determined in spermatozoa of 13 fertile subjects, 8 potentially fertile patients, and 12 infertile patients. CoQ10 concentrations were significantly higher (P < 0.001) in infertile patients than in fertile and potentially fertile subjects. The difference between potentially fertile and fertile subjects was also significant (P < 0.001). We propose that a decrease in consumption of CoQ10 in both infertile and potentially fertile populations is due to an autoregulatory mechanism of ATP production.

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عنوان ژورنال:
  • Clinical chemistry

دوره 41 2  شماره 

صفحات  -

تاریخ انتشار 1995